Philadelphia, Pa.: Churchill Livingstone Elsevier 2014. The presence of unequal pupil size may be a sign of a serious. New York, N.Y.: McGraw-Hill Education 2018. Causes range from life threatening to completely benign. In: Current Diagnosis & Treatment: Pediatrics. Treatment and prognosis of neuroblastoma. Clinical presentation, diagnosis, and staging evaluation of neuroblastoma. Another rare syndrome causes abdominal swelling and diarrhea. One paraneoplastic syndrome that occurs rarely in people with neuroblastoma causes rapid eye movements and difficulty with coordination. Neuroblastoma cells may secrete certain chemicals that irritate other normal tissues, causing signs and symptoms called paraneoplastic syndromes. Signs and symptoms caused by tumor secretions.
#UNEQUAL PUPIL SIZE BENIGN FULL#
View Full Report Show Less Print / Download as PDF. Spinal cord compression may cause pain and paralysis. When a persons pupils are of unequal size, the term anisocoria may be used. Tumors may grow and press on the spinal cord, causing spinal cord compression.
#UNEQUAL PUPIL SIZE BENIGN SKIN#
Neuroblastoma may spread (metastasize) to other parts of the body, such as the lymph nodes, bone marrow, liver, skin and bones. ComplicationsĬomplications of neuroblastoma may include: In most cases of neuroblastoma, a cause is never identified. Yet, familial neuroblastoma is thought to comprise a very small number of neuroblastoma cases. Risk factorsĬhildren with a family history of neuroblastoma may be more likely to develop the disease. It isn't clear what causes the initial genetic mutation that leads to neuroblastoma. Others, however, form a tumor - a neuroblastoma.
In most cases, these neuroblasts mature or disappear. Unequal size of pupils (anisocoria) often presents as a diagnostic challenge for clinicians because the underlying etiology may stem from a variety of factors 1. Most neuroblasts mature by birth, though a small number of immature neuroblasts can be found in newborns. Neuroblastoma begins in neuroblasts - immature nerve cells that a fetus makes as part of its development process.Īs the fetus matures, neuroblasts eventually turn into nerve cells and fibers and the cells that make up the adrenal glands. Anisocoria is a term used to refer to pupils that are of different sizes at any one time.Anisocoria can be because of an underlying medical condition or could be physiologic (normal). The accumulating abnormal cells form a mass (tumor). There are a variety of reasons your cat may have pupils that have different sizes. Typically, the size of your pupils should be similar in each eye, and both eyes should constrict or dilate together. Cancer cells grow and multiply out of control. In general, cancer begins with a genetic mutation that allows normal, healthy cells to continue growing without responding to the signals to stop, which normal cells do. Anisocoria is a condition characterized by an unequal size of the eyes pupils.
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